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Clinical trials for Vascular Resistance

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43871   clinical trials with a EudraCT protocol, of which   7290   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    248 result(s) found for: Vascular Resistance. Displaying page 1 of 13.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2008-005006-39 Sponsor Protocol Number: selene 2008 Start Date*: 2009-02-24
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Study on the vascular effects of ACE-I + CA-antagonist (Enalapril + Lercanidipine) versus ACE-I + diuretic (Enalapril + hydrochlorothiazidE) combinations in hypertensive patients with metabolic syn...
    Medical condition: hypertensive patients of either sex aged 40-69 years
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057166 HLGT
    9.1 10047065 SOC
    9.1 10047065 SOC
    9.1 10047065 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005759-21 Sponsor Protocol Number: Start Date*: 2011-04-21
    Sponsor Name:University of Oxford
    Full Title: Can atorvastatin improve vascular function in women with a history preeclampsia? A Randomised, double-blinded, placebo-controlled crossover trial of atorvastatin in women with a history of preeclam...
    Medical condition: Cardiovascular disease in women with a history of preeclampsia
    Disease: Version SOC Term Classification Code Term Level
    13.1 10047065 - Vascular disorders 10047063 Vascular disorder peripheral LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001525-28 Sponsor Protocol Number: ICL-INONAC1 Start Date*: 2006-03-24
    Sponsor Name:Imperial College London
    Full Title: INFLUENCE OF THE ANTIOXIDANT N-ACETYLCYSTEINE ON INHALED NITRIC OXIDE INDUCED PULMONARY RESPONSES FOLLOWING HUMAN LUNG ISCHAEMIA-REPERFUSION INJURY
    Medical condition: heart-lung transplantation
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-004600-17 Sponsor Protocol Number: T21 Start Date*: Information not available in EudraCT
    Sponsor Name:Royal College of Surgeons in Ireland
    Full Title: The use of Sildenafil in Neonates with Down Syndrome to Reduce Pulmonary Vascular Resistance.
    Medical condition: to assess the impact of oral sildenafil administration on echocardiography measurements of pulmonary vascular resistance in neonates with Down Syndrome without Congenital Heart Disease.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022891 - Investigations 10067285 Vascular resistance pulmonary increased PT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-010614-30 Sponsor Protocol Number: CH/2007/2746 Start Date*: 2009-05-08
    Sponsor Name:University Hospitals Bristol
    Full Title: Randomised cross-over pilot study to determine the effects of isoflurane and propofol on pulmonary vascular resistance in children with pulmoanry hypertension
    Medical condition: children with pulmonary hypertension
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2008-001835-36 Sponsor Protocol Number: 68923 Start Date*: 2008-07-09
    Sponsor Name:Gedeon Richter Plc.
    Full Title: Single center, exploratoric, open-label study to investigate the add-on effect of vinpocetin to the haemorheological effect of 100 mg acetyl-salicylicum in patients with chronic cerebrovascular dis...
    Medical condition: Aspirin resistance in patients with chronic cerebrovascular disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045652 Unspecified cerebrovascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-001562-16 Sponsor Protocol Number: RGHT000278 Start Date*: 2006-11-01
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: Studies of insulin action in patients at increased vascular risk. Modulation by antihypertensive and endocrine replacement therapy.
    Medical condition: Protocol (a): Essential Hypertension Protocol (b): Hypertension in Type 2 Diabetes Protocol (c): Panhypopituitarism
    Disease: Version SOC Term Classification Code Term Level
    8.1 10022489 Insulin resistance LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-005426-37 Sponsor Protocol Number: 4733 Start Date*: 2008-11-25
    Sponsor Name:University Medical Center Utrecht
    Full Title: The effect of sevoflurane and isoflurane on vasopressor need
    Medical condition: Aim of this study is to determine the effect of isoflurane versus sevoflurane on blood pressure and systemic vascular resistance.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005727 Blood pressure LLT
    9.1 10011978 Decreased systemic vascular resistance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003861-34 Sponsor Protocol Number: 0/2004 Start Date*: 2005-06-08
    Sponsor Name:Department of Nuclear Medicine
    Full Title: Influence of the PPAR gamma -agonist Pioglitazone on endothelial function in the peripheral and myocardial vascular territories and on myocardial efficiency in obese subjects
    Medical condition: There is an association between insulin resistance and endothelial dysfunction which is thought to be a critical factor in the development of vascular disease and thus an important factor in the de...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004139-66 Sponsor Protocol Number: AGO/2018/006 Start Date*: 2019-04-11
    Sponsor Name:Ghent University Hospital
    Full Title: Effect of norepinephrine infusion on hepatic blood flow during goal-directed hemodynamic therapy.
    Medical condition: hepatic blood flow hepatic vascular pressures
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001003-38 Sponsor Protocol Number: RGHT000540 Start Date*: 2008-08-01
    Sponsor Name:The Royal Group of Hospitals, Belfast Trust
    Full Title: A study investigating rimonabant versus placebo in conjunction with a strict low-fat weight reduction diet in overweight and obese subjects: effects on glucose and lipid metabolism and cardiovascul...
    Medical condition: This study will investigate subjects who are overweight and obese with Body Mass Index >27kg/m2.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022489 Insulin resistance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001232-42 Sponsor Protocol Number: RGHT000270 Start Date*: 2006-06-14
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: The Pharmacogenetics of Aspirin Resistance
    Medical condition: Aspirin resistance: Vascular diseases are common problems and aspirin is used as an anti-platelet drug to prevent thrombosis. However, aspirin's anti-platelet effect may not be uniform in all patie...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020875-22 Sponsor Protocol Number: MetSNS Start Date*: 2010-08-20
    Sponsor Name:RUNMC
    Full Title: In vivo induction of heme oxygenase-1 (HO-1) in the metabolic syndrome (MetS). Influence of heme arginate (Normosang) infusion on heme oxygenase-1 activity, endothelial dysfunction, insulin resista...
    Medical condition: Subjects suffer from the metabolic syndrome. Effects of study medication on insulin resistance and vascular function will be studied respectively.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022489 Insulin resistance LLT
    12.1 10052066 Metabolic syndrome LLT
    12.1 10048554 Endothelial dysfunction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-020698-17 Sponsor Protocol Number: 2010_3 Start Date*: 2010-10-04
    Sponsor Name:Antwerp University Hospital : Department Respiratory Medicine
    Full Title: Study of the vascular wall with functional imaging in OSA patients.
    Medical condition: Obstructive sleep apnea (OSA) is a prevalent disorder and characterised by sleepiness during the daytime, fatigue and impairments of concentration. OSA can also lead to cardiovascular pathology due...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003843-28 Sponsor Protocol Number: STH13565 Start Date*: 2005-03-18
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The acute effects of testosterone administration in patients with pulmonary hypertension
    Medical condition: Pulmonary Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000709-38 Sponsor Protocol Number: BBR Start Date*: 2015-10-20
    Sponsor Name:Medical University of Graz
    Full Title: Acute Effects of Benzbromaron on the pulmonary circulation
    Medical condition: Pulmonary arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023980-17 Sponsor Protocol Number: Metformin 3.0 Start Date*: 2011-08-24
    Sponsor Name:St. Antonius Hospital
    Full Title: An efficacy, safety and pharmacokinetic study on the short-term and long-term use of METFORMIN in obese children and adolescents
    Medical condition: obese children and adolescents of Caucasian descent with insulin resistance in the age of ≥ 10 and ≤ 16 years at study entry.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017176-25 Sponsor Protocol Number: WMLREC and BBC LREC Start Date*: 2010-09-08
    Sponsor Name:Sandwell and West Birmingham NHS Trust
    Full Title: Aspirin resistance and heart disease
    Medical condition: Index group 1 : coronary artery disease Index group 2: atrial fibrillation Control group 1: Diabetes/hypertension/hypercholesterolaemia Control group 2: Healthy subjects
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-023979-25 Sponsor Protocol Number: 2010/353 Start Date*: 2011-01-03
    Sponsor Name:Department of Nephrology
    Full Title: Role of renal and systemic vascular resistance for progression of chronic kidney disease
    Medical condition: We want to investigate whether increased vasodilitation ( angiotensin converting enzyme inhibitor and calcium channel blocker) compared to standard treatment ( beta-blocker and angiotensin convert...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10047065 - Vascular disorders 10063097 Peripheral vasodilatation LLT
    13.1 10047065 - Vascular disorders 10047141 Vasodilatation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001538-15 Sponsor Protocol Number: 6034 Start Date*: 2007-06-12
    Sponsor Name:Sangart Inc
    Full Title: A randomized, single-blind, controlled Phase II pilot study of Hemospan® compared with colloid (Voluven®) to evaluate vascular resistance and blood flow in the forearm, and to assess local skin blo...
    Medical condition: chronic critical limb ischemia (CCLI)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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